A Lysozyme Concentration, pH, and Time-Dependent Isothermal Transformation Diagram Reveals Fibrous Amyloid and Non-Fibrous, Amorphous Aggregate Species
نویسندگان
چکیده
منابع مشابه
A Lysozyme Concentration, pH, and Time-Dependent Isothermal Transformation Diagram Reveals Fibrous Amyloid and Non-Fibrous, Amorphous Aggregate Species
Deposition of aggregated protein is associated with many human diseases. The mechanism by which protein aggregate species cause cellular death remains unclear. A profile revealing protein aggregation products under a diverse set of conditions allows the search of novel aggregate products and potential pathogens. To achieve this end, an isothermal transformation diagram (ITD) of lysozyme aggrega...
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ژورنال
عنوان ژورنال: Open Journal of Biophysics
سال: 2014
ISSN: 2164-5388,2164-5396
DOI: 10.4236/ojbiphy.2014.42006