A Luciferase Immunoprecipitation System (LIPS) assay for profiling human norovirus antibodies

Antibody profiling by Luciferase Immunoprecipitation Systems (LIPS).

Technologies for comprehensively understanding and quantifying antibody profiles to autoantigens and infectious agents may yield new insights into disease mechanisms and may elucidate new markers to substratify disease with different clinical features and better understand pathogenesis. We have developed a highly quantitative method called Luciferase Immunoprecipitation Systems (LIPS) for profi...

luciferase immunoprecipitation system assay, a rapid, simple, quantitative, and highly sensitive antibody detection for parasitic diseases

no abstract

Novel detection of pancreatic and duodenal homeobox 1 autoantibodies (PAA) in human sera using luciferase immunoprecipitation systems (LIPS) assay.

We have previously identified pancreatic and duodenal homeobox 1 (Pdx1) autoantibodies (PAA) in sera from both non-obese diabetic (NOD) mice and human type 1 diabetic (T1D) patients. A suitable non-radioactive, sensitive and specific assay is needed for large-scale testing to determine the clinical utility of PAA. Here we reported a liquid-phase luciferase immunoprecipitation system (LIPS) assa...

Luciferase Immunoprecipitation System Assay, a Rapid, Simple, Quantitative, and Highly Sensitive Antibody Detection for Parasitic Diseases

tudying immunoglobulin responses by serological techniques is imperative for evaluating antibody titer values during the course of some parasitic infections. Therefore, the presence of a rapid, high-throughput, cost-effective and safe method, which can minimize both false positive-and false negativecases, is beneficial for early diagnosis and accurate treatment of patient. Accordingly, the aim ...

LightSwitchTM Luciferase Assay System