A lesion categorized between ghost cell odontogenic carcinoma and dentinogenic ghost cell tumor with CTNNB1 mutation
نویسندگان
چکیده
منابع مشابه
Disorganized histomorphology: Dentinogenic ghost cell tumor
Calcifying odontogenic cyst (COC) is a term used broadly to define lesions which were either cystic/solid in nature. However, a new term defining dentinogenic ghost cell tumor (DGCT), as its neoplastic counterpart, histopathologically showed the presence of dentinoid-like areas, ghost cells and ameloblastomatous-like odontogenic epithelium. This possesses a great challenge to an oral pathologis...
متن کاملDentinogenic Ghost Cell Tumor of the Peripheral Variant Mimicking Epulis
Dentinogenic ghost cell tumor (DGCT) is an uncommon locally invasive odontogenic tumor regarded by many as a variant of calcifying odontogenic cyst. The peripheral variant of this clinical rarity appears as a well-circumscribed mass mimicking a nonspecific gingival enlargement. Microscopic appearance of odontogenic epithelium admixed with focal areas of dentinoid formation and sheets of ghost c...
متن کاملGhost Cell Odontogenic Carcinoma Arising from Calcifying Cystic Odontogenic Tumor: A Case Report
Ghost cell odontogenic carcinoma (GCOC) is an exceptionally rare and malignant odontogenic tumor with aggressive growth characteristics. We describe a case of GCOC which was considerably derived from a previously resected calcifying cystic odontogenic tumor (CCOT). Cellular atypia, mitotic activity, Ki-67 labeling index and matrix metalloprotease-9 positive expression rate were all increased in...
متن کاملPediatric Metastatic Odontogenic Ghost Cell Carcinoma: A Multimodal Treatment Approach
Odontogenic ghost cell carcinoma (OGCC) is a rare and aggressive tumor wherein optimal treatment remains uncertain. We report the first pediatric metastatic OGCC case treated with multimodal therapy: surgery, adjuvant chemoradiation, and adjuvant immunotherapy. Adjuvant therapy was utilized due to locally advanced disease with pathologic features indicative of high recurrence risk. This multimo...
متن کاملAggressive Recurrent Odontogenic Ghost Tumor with Cranial Invasion.
Calcifying odontogenic cyst (COC) is a unique odontogenic lesion with combined features of a cyst and neoplasm. This lesion shows a great diversity in its clinicopathological behavior. It may become aggressive and rarely malignant. This case is an aggressive COC of the maxilla in a young male patient which recurred after several radical surgical excisions. Eventually invading the cranium, t...
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ژورنال
عنوان ژورنال: Pathology International
سال: 2018
ISSN: 1320-5463
DOI: 10.1111/pin.12659