A family case report of Neurofibromatosis

Neurofibromatosis is a genetic disease inherited in an autosomal, dominant manner. The course of von Recklinghausen’s varies from patient to patient. Most cases are mild and uncomplicated. diagnosis NF1 based on the criteria National Institutes Health (NIH). Type 2 neurofibromatosis inherited, most autosomal dominantly. abnormal allele can be either parent, with risk passing gene offspring being 50%. This article describes familial form neurofibromatosis. In case question, all three sisters were found mutated by testing. same family, clinical manifestation may different for children. Due compliance medical recommendations, does not significantly affect quality life families affected.