A distribution free summarization method for Affymetrix GeneChip(R) arrays
نویسندگان
چکیده
منابع مشابه
A Distribution Free Summarization Method for Affymetrix Genechip Data Preprocessing Analysis
Motivation: Affymetrix GeneChip brand arrays require a summarization step in order to combine the information in a probe set into one value representing the expression level of the corresponding gene. Here we present a new summarization method, Distribution Free Weighted (DFW) fold change, that uses the information of fold change but does not make any distributional assumptions for the data. Re...
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Exon arrays enable the monitoring of expression on a more fine-grained level than conventional 3' arrays. By targeting single exons alternative splicing events can be detected. However, the increased amount of data resulting from the denser coverage of the transcribed regions gives rise to new challenges in data analysis compared to 3' arrays. One must carefully decide which probes are consider...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2006
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btl609