A direct interaction between two Restless Legs Syndrome predisposing genes: MEIS1 and SKOR1

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Association between restless legs syndrome and migraine.

BACKGROUND An association between restless legs syndrome and migraine has been reported recently. The clinical correlates and impact of comorbidity of restless legs syndrome (RLS) are not fully described in patients with migraine. OBJECTIVES To investigate the frequency of RLS among different primary headache disorders, and its impact and clinical correlates in migraine patients. METHODS Co...

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The restless legs syndrome.

The first description of the restless legs syndrome (RLS) is attributed to Thomas Willis in the 'London Practice of Physick' of 1685 (Ekbom, 1960). Here he wrote 'wherefore to some, when being a bed they betake themselves to sleep, presently in the arms and leggs, leapings and contractions of their tendons, and so great a restlessness and tossings of their members ensue, that the diseased are n...

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Restless legs syndrome.

Restless legs syndrome is common; it is characterised by an urge to move and usually, but not exclusively, affects the legs. This urge to move is typically accompanied by abnormal sensations, variably described as burning, tingling, aching, or “insects crawling under the skin.” These sensations are transiently or partially relieved by movement, and there is a strong circadian influence—symptoms...

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[Restless legs syndrome].

The restless legs syndrome (RLS) is a common neurological disorder to take possession of increasing attention. RLS is characterized by an urge to move the legs, usually accompanied by uncomfortable or unpleasant sensations, that occurs or worsen at rest and is relieved by activity. The symptoms of RLS have a major impact on nocturnal sleep and daytime functions. The clinical diagnostic criteria...

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Restless legs syndrome (RLS)

Restless legs syndrome (RLS and also known as Willis-Ekbom disease) is a disorder that's characterized by annoying and sometimes painful sensations in the legs that are brought about by sitting or lying down. These sensations can include creeping, tingling, burning, tugging, or aching in the calves, thighs, or feet. Getting up and moving around is usually the only way to find some relief. Also,...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2018

ISSN: 2045-2322

DOI: 10.1038/s41598-018-30665-6