A DEHP plasticizer alters synaptic proteins via peroxidation
نویسندگان
چکیده
منابع مشابه
4-Heptanone is a metabolite of the plasticizer di(2-ethylhexyl) phthalate (DEHP) in haemodialysis patients.
BACKGROUND There is an ongoing discussion about the risks of di(2-ethylhexyl) phthalate (DEHP) exposure for the general population as well as for specific subgroups in various medical settings. Haemodialysis patients certainly belong to the group with the highest exposure taking into account the repeated treatments over a long period of time. Many studies have shown that DEHP metabolites are mo...
متن کاملLove Song Blues: DEHP Alters Courtship Vocalizations in Mice.
Due to its prevalence and known endocrine-disrupting properties, DEHP [di(2-ethylhexyl) phthalate] has been subject to extensive research into potential human health effects, especially related to the reproductive system.34 An article in Environmental Health Perspectives reports evidence that even small doses of DEHP may alter the courtship behavior of otherwise healthy adult male mice by reduc...
متن کاملToxicological quandary of the use of bis (2-diethylhexyl) phthalate (DEHP) as a plasticizer for blood bags.
Plastic bags are very useful containers for the storage of blood and blood products since they are relatively transparent, hard to break, can be sealed aseptically with a radio-frequency current, and can be centrifuged for the isolation of blood components. In order to make the plastic more flexible, various agents are added, of which the most common is di- (2-ethylhexyl) phthalate (DEHP). This...
متن کاملKindling alters the calcium/calmodulin-dependent phosphorylation of synaptic plasma membrane proteins in rat hippocampus.
Septal kindling was associated with an inhibition of the post hoc phosphorylation of several synaptic plasma membrane proteins of rat hippocampus. In control rats, the 32P incorporation into proteins of molecular weights 50,000, 58,000, and 60,000 was markedly stimulated by combined calcium/calmodulin, whereas in kindled animals, the response to combined calcium/calmodulin was reduced. Calcium ...
متن کاملDEHP Correction
A content of resin monomers and degradation prod-ucts[abstract]. EB, Lee-Chou L. In vitro elution of leachable components from dental sealants. The environmental estrogen bisphenol A stimulates prolactin release in vitro and in vivo. Profound effects of the weak environmental estrogen-like chemical bisphe-nol A on the growth of the mammary gland of Noble rats. Interference with microtubules and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Toxicology Research
سال: 2017
ISSN: 2045-452X,2045-4538
DOI: 10.1039/c6tx00361c