A Data-Adaptive Sum Test for Disease Association with Multiple Common or Rare Variants
نویسندگان
چکیده
منابع مشابه
A data-adaptive sum test for disease association with multiple common or rare variants.
Since associations between complex diseases and common variants are typically weak, and approaches to genotyping rare variants (e.g. by next-generation resequencing) multiply, there is an urgent demand to develop powerful association tests that are able to detect disease associations with both common and rare variants. In this article we present such a test. It is based on data-adaptive modific...
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ژورنال
عنوان ژورنال: Human Heredity
سال: 2010
ISSN: 1423-0062,0001-5652
DOI: 10.1159/000288704