A Cutaneous Clue to a Systemic Illness

Cutaneous blastomycosis: a clue to a systemic disease*

A 55-year-old male presented with back pain and slightly tender annular plaques with central ulceration on his face. A skin biopsy revealed scattered yeast with broad based buds. A CT scan of the abdomen revealed a pathologic T12 fracture. Tissue obtained from the spine confirmed budding yeasts. The patient was diagnosed with disseminated blastomycosis. The patient was treated with amphotericin...

Eschar: a cutaneous clue to scrub typhus.

60-year-oldmanpresentedwith a seven-day history of fever, eadache, fatigue, and decreased urine output. On examinaion, he was febrile (38 ◦C), and had tachycardia. A blackish kin lesion was noted on the right side of his neck (Fig. 1). scharwas not preceded by any pain or itching. His hemogram evealed a hemoglobin count of 11.8 gm/dL, total leukocyte ount of 6300/mm3, and a platelet count of 80...

Cutaneous manifestations of systemic Lupus Erythematosus: A study from Ahwaz

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease in which cutaneous lesions occur in 72%-85% of patients. Objective: This study was conducted to determine the pattern and incidence of skin lesions in SLE patients in Ahwaz. Patients and Methods: Thirty patients with SLE fulfilling the clinical and laboratory criteria of the American Rheumatism Association who were admitted...

Orthostatic hypotension as a clue to primary systemic amyloidosis.

Methods We reviewed the records of 138 patients with primary systemic amyloidosis seen at the Mayo Clinic from 1935 through 1964. In all instances, the presence of amyloidosis was proved by tissue biopsy or postmortem examination. The criteria for the diagnosis of orthostatic hypotension included a decrease in the standing blood pressure from the recumbent blood pressure of 30 mm Hg systolic an...

Recurrent Acute Pancreatitis: A Diagnostic Clue to Primary Hyperparathyroidism