A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior

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Several lines of evidence suggest that a hypoglutamatergic condition may induce a phenotypic loss of cortical parvalbumin (PV)-positive GABAergic interneurons, such as that observed in brain tissue of schizophrenic subjects. However, it is not known whether the loss of PV interneurons is a consequence of the hypoglutamatergic condition or a secondary aspect of the disease. We characterized the ...

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ژورنال

عنوان ژورنال: Molecular Psychiatry

سال: 2011

ISSN: 1359-4184,1476-5578

DOI: 10.1038/mp.2011.31