A Controlled Release Theophylline Delivery System Based on a Bilayer Floating System
نویسندگان
چکیده
منابع مشابه
A Review on Floating Drug Delivery System
Management of infirmity through medication is entering a new era in which growing number of novel drug delivery systems are being employed and are available for therapeutic use. Oral sustained release gastro-retentive dosage forms (GRDFs) offer many advantages for drugs with absorption from upper parts of gastrointestinal tract and for those acting locally in the stomach, improving the bioavail...
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چکیده ندارد.
15 صفحه اولIn vitro-in vivo correlation studies on a novel controlled release theophylline delivery system and on Theo-Dur tablets
A good correlation should be obtained between data derived from in vitro dissolution and bioavailability studies on drug delivery systems if bioavailability parameters are to be reliably predicted from the in vitro dissolution variables. This study compares the in vivo absorption with the in vitro dissolution profiles into various dissolution media of a novel controlled release theophylline cap...
متن کاملPreparation and In Vitro Evaluation of a Microballoon Delivery System for Theophylline
A multiple-unit oral floating system was prepared using the emulsification-solvent diffusion method to prolong the gastric emptying time of theophylline. For this purpose, theophylline, ethyl cellulose and dibutyl phthalate were dissolved in an ethanol/dichloromethane mixture, added to 0.1 M HCl containing NaCl (20%) or saturated theophylline and/or different concentrations of polysorbate 80 an...
متن کاملPreparation and In Vitro Evaluation of a Microballoon Delivery System for Theophylline
A multiple-unit oral floating system was prepared using the emulsification-solvent diffusion method to prolong the gastric emptying time of theophylline. For this purpose, theophylline, ethyl cellulose and dibutyl phthalate were dissolved in an ethanol/dichloromethane mixture, added to 0.1 M HCl containing NaCl (20%) or saturated theophylline and/or different concentrations of polysorbate 80 an...
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ژورنال
عنوان ژورنال: Turkish Journal of Pharmaceutical Sciences
سال: 2020
ISSN: 1304-530X,2148-6247
DOI: 10.4274/tjps.galenos.2019.53325