A competitive hybridization model predicts probe signal intensity on high density DNA microarrays
نویسندگان
چکیده
منابع مشابه
A competitive hybridization model predicts probe signal intensity on high density DNA microarrays
A central, unresolved problem of DNA microarray technology is the interpretation of different signal intensities from multiple probes targeting the same transcript. We propose a competitive hybridization model for DNA microarray hybridization. Our model uses a probe-specific dissociation constant that is computed with current nearest neighbor model and existing parameters, and only four global ...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2008
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkn740