A comparison of three techniques to estimate the human dark-adapted cone electroretinogram

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A comparison of three techniques to estimate the human dark-adapted cone electroretinogram

The dark-adapted cone electroretinogram (ERG) is difficult to isolate because of unwanted rod intrusion. We compare dark-adapted cone estimates derived using three techniques. The first uses the cone response on a moderate rod saturating background to estimate the dark-adapted cone response. The second uses red and blue flashes to tease apart cone and rod responses (red-minus-blue technique, [I...

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[Characteristics of dark-adapted and light-adapted oscillatory potentials in human electroretinogram].

OBJECTIVE To characterize dark-adapted and light-adapted oscillatory potentials (OPs) in human electroretinogram (EGR) elicited by flashing light stimulation of the same intensity. METHODS Dark- and light-adapted ERGs of normal eyes were studied. The frequency spectra of the extracted dark-adapted OPs and light-adapted OPs were analyzed by a fast Fourier transform. The peak frequency, latency...

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Senescent Changes and Topography of the Dark-Adapted Multifocal Electroretinogram

Purpose To investigate the topographic changes of the dark-adapted multifocal electroretinogram (mfERG) across adulthood in the central retina and compare the topography between macular versus extramacular, nasal versus temporal, and inferior versus superior retinal areas. Methods Sixty-five subjects (18-88 years) received a comprehensive dilated eye examination to ensure the health of their ...

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Contribution of rod and cone pathways to the dark-adapted electroretinogram (ERG) b-wave following retinal degeneration in RCS rats

Although the RCS rat is widely used as a model of progressive photoreceptor loss, it is unclear how the relative rod and cone functions change with age. Rod and cone b-waves were isolated using a double flash ERG paradigm. In contrast to cones, rods never reached normal functional maturity levels, and the ERG b-wave changed from being predominantly rod-driven to being purely cone-driven by age ...

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ژورنال

عنوان ژورنال: Vision Research

سال: 2003

ISSN: 0042-6989

DOI: 10.1016/s0042-6989(03)00330-4