A Comparison between the Effects of Glucantime, Topical Trichloroacetic Acid 50% plus Glucantime, and Fractional Carbon Dioxide Laser plus Glucantime on Cutaneous Leishmaniasis Lesions

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A Comparison between the Effects of Glucantime, Topical Trichloroacetic Acid 50% plus Glucantime, and Fractional Carbon Dioxide Laser plus Glucantime on Cutaneous Leishmaniasis Lesions.

Background. Cutaneous leishmaniasis is an endemic disease in Iran. Pentavalent antimonial drugs have been the first line of therapy in cutaneous leishmaniasis for many years. However, the cure rate of these agents is still not favorable. This study was carried out to compare the efficacies of intralesional glucantime with topical trichloroacetic acid 50% (TCA 50%) + glucantime and fractional ca...

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Comparison between intralesional Glucantime plus steroid and Glucantime in the treatment of cutaneous leishmaniasis

Introduction: Cutaneous leishmaniasis is a parasitic disease caused by various Leishmaniasis species and can result in a disfiguring scar. Hence, effective treatment is mandatory for prevention of the disease sequellae. The goal of this study was assessment and comparison of intralesional Glucantime plus steroid with intralesional Glucantime in the treatment of cutaneous leishmaniasis. Method...

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The Evaluation of Intralesional Glucantime and Cryotherapy plus Intralesional Glucantime Therapeutic Efficacy on Zoonotic Cutaneous Leishmaniasis: A Randomized Clinical Trial

Background: Currently, Glucantime is considered the first-line treatment of cutaneous Leishmaniasis. This study aimed to evaluation of intralesional Glucantime (IG) and Cryotherapy (Cryo) plus intralesional Glucantime (Cryo and IG) therapeutic efficacy on Zoonotic Cutaneous Leishmaniasis in Qom province, Iran. Materials and Methods: In this randomized controlled trial of 197 CL patients reporte...

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The Efficacy of Co-administration of Topical Niosomal Dapsone Gel and Intralesional Injection of Glucantime in Cutaneous Leishmaniasis in Comparison with Cryotherapy Plus Intralesional Injection of Glucantime

Background & Aims: Leishmaniasis exists in more than half of Iran provinces and more than 20,000 cases are reported annually. In the recent years, several therapeutic approaches such as topical and physical treatments have been investigated. In the present study, the efficacy of co-administration of topical Niosomal Dapsone gel and Glucantime intralesional injection has been evaluated. Method: ...

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The therapeutic effect of ozonated olive oil plus glucantime on human cutaneous leishmaniasis

Objective(s): Leishmaniasis is one of the main health problems in developing countries, caused by intracellular protozoan parasites of the Leishmania genus. Although research has been successful in discovering vaccines and anti-parasitic drugs like antimony compounds, their side effects like high toxicity, prolonged regeneration, etc., have raised the replacement importance of natural products ...

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ژورنال

عنوان ژورنال: Dermatology Research and Practice

سال: 2016

ISSN: 1687-6105,1687-6113

DOI: 10.1155/2016/6462804