A clinical and echocardiographic score to differentiate pulmonary hypertension due to heart failure with preserved ejection fraction from idiopathic pulmonary hypertension: the PH-HFPEF score

Capillary pCO2 helps distinguishing idiopathic pulmonary arterial hypertension from pulmonary hypertension due to heart failure with preserved ejection fraction

RATIONALE The demographics of patients with idiopathic pulmonary arterial hypertension (IPAH) are changing and this diagnosis is increasingly being made in older patients. However, diagnostic misclassifications are common as it may be difficult to differentiate between IPAH and pulmonary hypertension due to heart failure with preserved ejection fraction (PH-HFpEF). We investigated the hypothesi...

Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction: Clinical Relevance, Management, and Future Directions

Thenappan Thenappan, MD Cardiovascular Division Department of Medicine University of Minnesota Medical School Minneapolis, MN There are currently 6 million Americans with heart failure, and this number is projected to increase to 8.5 million by 2030. One-half of patients with heart failure have preserved ejection fraction (HFpEF), and the prevalence is increasing. HFpEF can lead to secondary pu...

[Heart failure with preserved ejection fraction (HFpEF)].

Pulmonary Hypertension Is Related to Peripheral Endothelial Dysfunction in Heart Failure With Preserved Ejection Fraction Farrero et al: Endothelium and Pulmonary Hypertension in HFpEF

B i p Med ed ed ed edicine De e ep par rt tm ment nt nt t t, Pn n neu u umo ol logy g gy, Abstract Background—Pulmonary hypertension and collagen metabolism abnormalities are

Clinical characteristics of pulmonary hypertension in patients with heart failure and preserved ejection fraction.

BACKGROUND Pulmonary vascular disease associated with left-side heart failure and preserved ejection fraction (PH-HFpEF) is an increasingly common cause of pulmonary hypertension. The distinction between PH-HFpEF and pulmonary arterial hypertension (PAH) is important because therapies indicated for PAH can be detrimental in HFpEF. The characteristic features of PH-HFpEF are understudied. METH...