A chloride channel from lobster walking leg nerves. Characterization of single-channel properties in planar bilayers.
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چکیده
منابع مشابه
A chloride channel from lobster walking leg nerves. Characterization of single-channel properties in planar bilayers
A novel, small conductance of Cl- channel was characterized by incorporation into planar bilayers from a plasma membrane preparation of lobster walking leg nerves. Under conditions of symmetrical 100 mM NaCl, 10 mM Tris-HCl, pH 7.4, single Cl- channels exhibit rectifying current-voltage (I-V) behavior with a conductance of 19.2 +/- 0.8 pS at positive voltages and 15.1 +/- 1.6 pS in the voltage ...
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Alkaloid-modified, voltage-dependent sodium channels from lobster walking leg nerves were studied in planar neutral lipid bilayers. In symmetrical 0.5 M NaCl the single channel conductance of veratridine (VTD) (10 pS) was less than that of batrachotoxin (BTX) (16 pS) modified channels. At positive potentials, VTD- but not BTX-modified channels remained open at a flickery substate. VTD-modified ...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1990
ISSN: 0022-1295,1540-7748
DOI: 10.1085/jgp.96.4.707