A Case of DiHSS/DRESS Syndrome-Related Acute Hepatic Failure

نویسندگان

چکیده

‘Drug Induced Hypersensitivity Syndrome’ (DiHS) or Rash with Eosinophilia and Systemic Symptoms’ (DRESS) syndrome is a life threatening, delayed type drug hypersensitivity reaction. This characterized by fever, skin rash, lymphadenopathy, hematological abnormalities visceral involvement liver the most frequently involved organ. Liver mostly presented as acute anicteric hepatitis elevated enzymes. Rarely, it can be cholestasis which indicates worse prognosis. In this article, case of valproic acid induced-DRESS who hepatic failure presented. Diagnosis DRESS may delay due to long interval between intake onset symptoms. The variety symptoms also challenging. Early diagnosis important in terms reducing morbidity mortality.

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ژورنال

عنوان ژورنال: Türkiye çocuk hastal?klar? dergisi

سال: 2022

ISSN: ['1307-4490', '2148-3566']

DOI: https://doi.org/10.12956/tchd.999501