A case of D-Penicillamine induced polymyositis
نویسندگان
چکیده
منابع مشابه
Polymyositis complicating D-penicillamine treatment.
Although there is good evidence that D-penicillamine can induce polymyositis, the exact pathogenic mechanism remains unclear. We report two patients with psoriatic arthritis and primary biliary cirrhosis respectively, who developed polymyositis while receiving D-penicillamine treatment for their primary diseases. Whether D-penicillamine treatment was the sole cause of polymyositis or acted as a...
متن کاملA Case of Polymyositis in a Patient with Primary Biliary Cirrhosis Treated with D-Penicillamine
Although D-penicillamine has been used for many rheumatologic diseases, toxicity limits its usefulness in many patients. Polymyositis/dermatomyositis can develop as one of the autoimmune complications of D-penicillamine treatment, but its exact pathogenesis remains unclear. We report a patient with primary biliary cirrhosis, who developed polymyositis while receiving D-penicillamine therapy. We...
متن کاملD-Penicillamine induced myasthenia gravis.
Myasthenia gravis is a disorder of impaired neuromuscular transmission resulting in weakness and abnormal fatigability on exertion, improved by anti-acetyl cholinesterase drugs. A number of drugs are known to exacerbate myasthenia gravis or interfere with neuromuscular transmission. We report a case of D-penicillamine induced myasthenia gravis who developed ptosis, diplopia and easy fatigabilit...
متن کاملD-penicillamine Induced Myasthenia Gravis
Rheumatoid arthritis can be a very mutilating disease and, as a result, the likelihood of patients with rheumatoid arthritis requiring surgery and anaesthesia is increased. D-penicillamine (D-Pen) has been used in the treatment of rheumatoid arthritis and Wilson's disease since the early 1960s. Its true mode of action is unknown, but it appears to modify the immune response. Treatment with D-Pe...
متن کاملA case of penicillamine-induced dermopathy.
INTRODUCTION We describe an interesting patient with penicillamine-induced dermopathy. CLINICAL PICTURE A 49-year-old woman presented with a 1-year history of recurrent haemorrhagic blisters, milia and purpura over both her elbows, while on long-term penicillamine therapy (1.5 g daily) for Wilson's disease. Histologically, dermal elastin fibres were markedly reduced in the affected areas, con...
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ژورنال
عنوان ژورنال: Japanese Journal of Clinical Immunology
سال: 1985
ISSN: 0911-4300,1349-7413
DOI: 10.2177/jsci.8.374