A case of Bence Jones (λ) type multiple myeloma, presenting multiple cutaneous lesions

Multiple Myeloma Presenting as Respiratory Stridor

Extramedullary plasmacytoma occurs in 18% of patients with multiple myeloma. Laryngeal involvement in multiple myeloma is rare, and only a few cases have been reported. We present a case of a 44-year-old women with multiple myeloma who presented with stridor due to a mass involving the larynx which was initially proven to be plasmacytoma on biopsy. She had evidence of multiple myeloma of IgA la...

Bence Jones proteinuria in multiple sclerosis.

We report our findings of Bence Jones proteins (monoclonal free light chains of immunoglobulins) in concentrated urines of patients with multiple sclerosis, by using agarose electrophoresis and immunofixation. The lack of such findings in urines from healthy subjects and patients with other neurological disorders should stimulate further investigation.

Bence-jones Proteinemia in Multiple Myelomai

The term "Bence-Jones protein" refers to an ill-defined group of proteins having a molecular weight of approximately 37,000 (1), and the characteristic properties of precipitating out of solution when warmed to 45 to 58° C. and of redissolving completely or partially on boiling. This peculiar behavior on heating has long served as a useful test for Bence-Jones proteins in the urine of patients ...

Melphalan and Antigenic Type of Bence-jones Proteins in Myeloma.

averaged many times (up to 100 times) a peak of activity could sometimes be observed to correspond with the minimum or the maximum intensity of light, according to the cell type ("off cells" or "on cells," respectively). The shape of the response, however, remained completely chaotic. An example of these results is shown in Fig. 1. Control experiments showed that the response of the retinal gan...

Two Bence Jones proteins of different immunologic types in the same patient with multiple myeloma.