A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors
نویسندگان
چکیده
منابع مشابه
Adrenergic receptors and metabolism: role in development of cardiovascular disease
Activation of the adrenergic system has a profound effects on metabolism. Increased circulating catecholamine and activation of the different adrenergic receptors deployed in the various organs produce important metabolic responses which include: (1) increased lipolysis and elevated levels of fatty acids in plasma, (2) increased gluconeogenesis by the liver to provide substrate for the brain, a...
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THE CONCEPT that drugs react with specific receptors in living tissues to produce pharmacologic effects is believed to have originated with Langley in 19051 although Ehrlich and others had certainly conceived of specific drug-cellular interactions. Today receptors have achieved such status amnong pharmacologists to be almost commonplace in spite of the fact that their identity has not been esta...
متن کاملAdrenergic Receptors Within the Cardiovascular System
THE CONCEPT that drugs react with specific receptors in living tissues to produce pharmacologic effects is believed to have originated with Langley in 19051 although Ehrlich and others had certainly conceived of specific drug-cellular interactions. Today receptors have achieved such status amnong pharmacologists to be almost commonplace in spite of the fact that their identity has not been esta...
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ژورنال
عنوان ژورنال: Cell
سال: 2020
ISSN: 0092-8674
DOI: 10.1016/j.cell.2020.02.016