A Brief Insight to the Electrophoretic Deposition of PEEK-, Chitosan-, Gelatin-, and Zein-Based Composite Coatings for Biomedical Applications: Recent Developments and Challenges

Electrophoretic deposition (EPD) is a powerful technique to assemble metals, polymer, ceramics, and composite materials into 2D, 3D, intricately shaped implants. Polymers, proteins, peptides can be deposited via EPD at room temperature without affecting their chemical structures. Furthermore, being used deposit multifunctional coatings (i.e., bioactive, antibacterial, biocompatible coatings). Recently, was architect multi-structured improve mechanical biological properties along with the controlled release of drugs/metallic ions. The key characteristics in terms inorganic bioactivity angiogenic potential coupled antibacterial are elements enabling advanced applications orthopedic applications. In emerging field for hard tissue soft engineering, an overview such will presented. progress development EPD-based polymeric or coatings, including application targeted drug delivery approaches, discussed, focus on effect different biologically active ions/drugs released from deposits. literature under discussion involves consisting chitosan (Chi), zein, polyetheretherketone (PEEK), composites. Moreover, vitro vivo investigations discussed relation current main challenge implants, namely that biomaterial must provide good bone-binding ability compatibility.