A biodegradable ocular implant for long-term suppression of intraocular pressure
نویسندگان
چکیده
منابع مشابه
Biocompatibility and long-term toxicity of InnoPol implant, a biodegradable polymer scaffold.
InnoPol, a poly((D,L)-lactic-co-glycolic acid) [PLGA] 65/35 scaffold manufactured by special gas foaming methods in Korea, was subjected to tests to evaluate the degradation and tissue compatibility characteristics and long-term systemic toxicity in mice and rats. C57BL/6 mice and SD rats were implanted subcutaneously with 3-mm- and 1-mm-thick InnoPol circular discs, 10 mm in diameter, respecti...
متن کاملIntraocular pressure and ocular rigidity after LASIK.
PURPOSE To assess the intraocular pressure (IOP) and ocular rigidity (E) at 1, 3, 6 and 24 postoperative months in eyes that underwent LASIK. METHODS The IOP measured by Goldmann applanation tonometer (GAT) and by the 5.5 and 10 gm. weights of a standardized Schioetz tonometer (ST) and the E measured by differential tonometry (the 5.5 and 10 gm. of ST) were assessed before and after LASIK (at...
متن کاملEffect of hemodialysis on intraocular pressure and ocular perfusion pressure.
IMPORTANCE Elevated intraocular pressure (IOP) and decreased ocular perfusion pressure (OPP) are risk factors for glaucoma development and progression. Unrecognized significant IOP elevation or OPP reduction during hemodialysis (HD) could lead to glaucomatous optic nerve damage and subsequent visual loss. OBJECTIVE To evaluate changes in IOP and OPP during HD. DESIGN, SETTING, AND PARTICIPA...
متن کاملIntraocular pressure and ocular perfusion during hemodialysis Pressão intraocular e perfusão ocular durante hemodiálise
Objetivo: Avaliar a pressão intraocular e a pressão de perfusão ocular durante uma sessão de hemodiálise. Métodos: Sessenta e sete olhos de trinta e cinco pacientes foram avaliados no início, após 2 horas e após 4 horas do início de uma sessão de hemodiálise. A pressão intraocular foi avaliada usando o aparelho Tonopen. Pressões arteriais sistólica e diastólica foram aferidas usando esfigmomanô...
متن کاملDetermination of Central Venous Pressure from Intraocular Pressure
Background: In many clinical situations, knowledge of central venous pressure (CVP) is important. Measurement of CVP is not always possible. Objective: To determine if intraocular pressure (IOP) can be used as an estimate for CVP. Methods: IOP and CVP were measured concurrently in 30 candidates of coronary artery bypass graft surgery. Those with carotid artery or jugular venous diseases as we...
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ژورنال
عنوان ژورنال: Drug Delivery and Translational Research
سال: 2015
ISSN: 2190-393X,2190-3948
DOI: 10.1007/s13346-015-0240-4