A Bayesian approach for estimating calibration curves and unknown concentrations in immunoassays

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چکیده

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A Bayesian approach for estimating calibration curves and unknown concentrations in immunoassays

MOTIVATION Immunoassays are primary diagnostic and research tools throughout the medical and life sciences. The common approach to the processing of immunoassay data involves estimation of the calibration curve followed by inversion of the calibration function to read off the concentration estimates. This approach, however, does not lend itself easily to acceptable estimation of confidence limi...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2012

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/bts136