A Balance Equation Determines a Switch in Neuronal Excitability
نویسندگان
چکیده
منابع مشابه
A Balance Equation Determines a Switch in Neuronal Excitability
We use the qualitative insight of a planar neuronal phase portrait to detect an excitability switch in arbitrary conductance-based models from a simple mathematical condition. The condition expresses a balance between ion channels that provide a negative feedback at resting potential (restorative channels) and those that provide a positive feedback at resting potential (regenerative channels). ...
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The neuronal components of brain circuitry are generally considered “stable” throughout an animals’ life; with the exception of times of growth and degeneration that occur during development, aging, or pathology. To maintain this stability, neurons must achieve a balance between changing output to meet new requirements, and keeping output within a satisfactory operating range. This balancing ac...
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ژورنال
عنوان ژورنال: PLoS Computational Biology
سال: 2013
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1003040