A 3D neurons model to evaluate the neurotoxicity of harmane, a β carboline alkaloid incriminated in Essential Tremor
نویسندگان
چکیده
منابع مشابه
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15 صفحه اولRelationship between blood harmane and harmine concentrations in familial essential tremor, sporadic essential tremor and controls.
INTRODUCTION Harmane, a potent tremor-producing β-carboline alkaloid, may play a role in the etiology of essential tremor (ET). Blood harmane concentrations are elevated in ET cases compared with controls yet the basis for this elevation remains unknown. Decreased metabolic conversion (harmane to harmine) is one possible explanation. Using a sample of >500 individuals, we hypothesized that defe...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2019
ISSN: 1662-453X
DOI: 10.3389/conf.fnins.2019.96.00076