A 34,000 dalton protein located in the Z-disk.
نویسندگان
چکیده
منابع مشابه
Unraveling Enigma in the Z-Disk
The Z-disk, a fascinating structure in myofibrils, demarcates sarcomeres and serves as not only a mechanical focal point but also a likely signaling nexus in mediating and regulating the functions of striated muscle. In the Z-disk, the barbed end of actin filaments and the titin filaments from the 2 opposing sarcomeres are cross-linked primarily by -actinin, allowing transmission of tension bet...
متن کاملLocalization of Z-protein in isolated Z-disk sheets of chicken leg muscle
Immunoblotting studies with antisera against Z-protein, desmin, and alpha-actinin showed that Z-protein is clearly distinguishable from desmin and alpha-actinin. Z-protein is not a proteolytic product of another protein but is an intrinsic component of chicken breast muscle myofibrils. In these experiments, an SDS extract of intact muscle was first electrophoresed in a polyacrylamide gel, and t...
متن کاملDisk galaxies at z=2 in OWLS
We use the OWLS (OverWhelmingly Large Simulations) set of cosmological Nbody/gasdynamical simulations to study the properties of simulated galaxies at z = 2. We focus on the effect of supernova feedback from evolving stars on the baryonic mass and angular momentum content of galaxies that assemble at the center of 10-10 hM⊙ halos. Our main finding is that the mass and angular momentum of such g...
متن کاملMutations in NEBL encoding the cardiac Z-disk protein nebulette are associated with various cardiomyopathies.
INTRODUCTION Transgenic mice overexpressing mutated NEBL, encoding the cardiac-specific Z-disk protein nebulette, develop severe cardiac phenotypes. Since cardiomyopathies are commonly familial and because mutations in a single gene may result in variable phenotypes, we tested the hypothesis that NEBL mutations are associated with cardiomyopathy. MATERIAL AND METHODS We analyzed 389 patients,...
متن کاملObservations on Organization of Z-disk Components and on Rod-bodies of Z-disk Origin
Current concepts of Z-disk fine structure are based on studies by Knappeis and Carlsen (1), FranziniArmstrong and Porter (2), Reedy (3), and Kelly (4) . Knappeis and Carlsen found that I filaments terminated adjacent to the disk and, in cross-section, were positioned in corners of I squares with 220 f 35 A sides . Each I filament from one side of the disk faced the geometric center of the space...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1982
ISSN: 0002-1369,1881-1280
DOI: 10.1271/bbb1961.46.1977