A 30 s test for quantitative assessment of a relative afferent pupillary defect (RAPD): the infrared pupillary asymmetry (IPA)

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How to test for a relative afferent pupillary defect (RAPD)

Light source The ‘swinging light test’ is used to detect a relative afferent pupil defect (RAPD): a means of detecting differences between the two eyes in how they respond to a light shone in one eye at a time. The test can be very useful for detecting unilateral or asymmetrical disease of the retina or optic nerve (but only optic nerve disease that occurs in front of the optic chiasm). The phy...

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Isolated relative afferent pupillary defect secondary to contralateral midbrain compression.

BACKGROUND Relative afferent pupillary defects are typically related to ipsilateral lesions within the anterior visual pathways. OBJECTIVE To describe a patient who had a workup for headache and was found to have an isolated left relative afferent pupillary defect without any other neurological findings. DESIGN We review the neuroanatomy of the pupillary light reflex pathway and emphasize t...

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Afferent pupillary defect in pineal region tumour.

A patient is described in whom an afferent pupillary defect was an early sign of a tumour in the pineal region. It is suggested that this was due to involvement of the pupillary afferent fibres between the optic tract and pretectal nucleus contralateral to the affected pupil.

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Quantification of optic nerve axon loss associated with a relative afferent pupillary defect in the monkey.

OBJECTIVE To quantify the amount of optic nerve axonal loss associated with the presence of a mild relative afferent pupillary defect (RAPD) in an experimental monkey model. METHODS The right macula of 5 rhesus monkeys (Macaca mulatta) was treated with concentrically enlarging diode laser burns until an RAPD was detected using a transilluminator light and measured with neutral density filters...

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Retinal nerve fiber layer loss in glaucoma patients with a relative afferent pupillary defect.

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ژورنال

عنوان ژورنال: Journal of Neurology

سال: 2019

ISSN: 0340-5354,1432-1459

DOI: 10.1007/s00415-019-09223-1