945-622 Impaired Heart Rate Response to Graded Exercise: Prognostic Implications of Chronotropic Incompetence

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Impaired heart rate recovery and chronotropic incompetence in patients with heart failure with preserved ejection fraction.

BACKGROUND This study assessed the chronotropic response to exercise and heart rate (HR) recovery after exercise in a carefully phenotyped group of patients with heart failure with preserved left ventricular ejection fraction (HfpEF) and a control group of similar age and gender distribution. METHODS AND RESULTS We studied 41 patients with HfpEF, 41 healthy controls, and 16 hypertensive contr...

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Chronotropic incompetence in heart failure.

The relationship between heart rate (HR) during exercise and exercise capacity in patients with heart failure due to left ventricular systolic dysfunction remains unclear. The accepted diagnostic criterion for chronotropic incompetence (CI), a maximum agepredicted heart rate (MA-PHR) 85%, is seen in 50% of patients with severe heart failure on contemporary medical therapy (1). Whether the lesse...

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Impaired chronotropic response to physical activities in heart failure patients

BACKGROUND While exercise-based cardiac rehabilitation has a beneficial effect on heart failure hospitalization and mortality, it is limited by the presence of chronotropic incompetence (CI) in some patients. This study explored the feasibility of using wearable devices to assess impaired chronotropic response in heart failure patients. METHODS Forty patients with heart failure (left ventricu...

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Impaired Chronotropic Response to Exercise in Patients With Congestive Heart Failure

The mechanism responsible for the attenuated heart rate (HR) response to exercise in patients with congestive heart failure (CHF) was investigated in 46 normal subjects and 59 patients with CHF stratified by peak exercise oxygen consumption (Vo2). The peak exercise HR and the increment in HR from rest to peak exercise were decreased in CHF patients, and both correlated strongly with peak Vo2 (r...

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Echocardiographic predictors of chronotropic incompetence to exercise in patients with heart failure with preserved ejection fraction.

OBJECTIVE Exercise intolerance in patients with heart failure with preserved ejection fraction (HFpEF) is most often attributed to diastolic dysfunction (DD); however, chronotropic incompetence (CI) could also play an important role. We intended to examine whether there are predictive echocardiographic parameters of DD for impaired chronotropic response to exercise. METHODS AND RESULTS Patien...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 1995

ISSN: 0735-1097

DOI: 10.1016/0735-1097(95)92167-4