899 EXTRAGONADAL ENDODERMAL SINUS TUMOR IN EARLY CHILDHOOD: TREATMENT RESPONSE AND LONGTERM EFFECT

Retroperitoneal extragonadal endodermal sinus tumor with bilateral diffuse classic testicular microlithiasis.

Endodermal Sinus Tumor of Vagina in Infants

Endodermal sinus tumor (or Yolk Sac tumor) of the vagina is a rare malignant germcell tumor which is seen exclusively in children younger than 3 years of age. We report two cases of endodermal sinus tumor of the vagina. In both cases no radiological investigation was done and serum alpha-fetoprotein was elevated. The histopathological examination of both the tumor masses revealed vaginal endode...

Treatment of ovarian endodermal sinus tumor to preserve fertility.

Endodermal sinus tumor, also known as yolk sac tumor (YST), is a malignant germ cell tumor that most frequently occurs in the testis, the ovary, and sacrococcygeal areas in children. YSTs are highly aggressive and because of the early metastatic or invasive pattern, their prognosis has been poor. Treatment methods for YSTs are usually intensive, including multiagent chemotherapy, and have shown...

Conservative management of primary vaginal endodermal sinus tumor and rhabdomyosarcoma

The aim of this study was to evaluate the conservative management and prognosis of primary vaginal endodermal sinus tumor and rhabdomyosarcoma in children. Medical records of children with vaginal endodermal sinus tumor and rhabdomyosarcoma between 1996 and 2015 were reviewed. A total of 24 patients (median age, 12 months; range, 7-44 months) were included in this study, comprising 17 patients ...

Endodermal sinus tumor of the vagina in a child.

Malignant germ cell tumors are rare tumors of the childhood accounting for less than 3 % of pediatric malignancies. Endodermal sinus tumor (EST) is the most common histologic subtype of malignant GCT. The vagina is an extremely rare site for GCTs [1]. They are usually diagnosed before 3 years of age. Historically, the approach to therapy has included radical surgical resection with adjuvant irr...