839 The association between early breastfeeding cessation and postpartum depressive symptoms among women intending to breastfeed

An association between sustained breastfeeding and a decrease in postpartum depression has been identified. However, over half of US women cease earlier than desired. Our objective was to evaluate whether early cessation is associated with depressive symptoms identified mental health conditions. This retrospective cohort study included enrolled an outpatient collaborative care perinatal program (COMPASS) during pregnancy reported intent breastfeed at delivery 02/2017-02/2020. Women were referred COMPASS either due history conditions or incident concerns. completed validated screens [Patient Health Questionnaire-9 (PHQ-9)] the visit. Scores compared who intended but exclusively formula feeding visit continued breastfeeding. Worsening defined as increase one standard deviation (i.e. 5 more) on PHQ-9 2nd 3rd trimester screen screen, antidepressant medication requirement, subjective report worsening mood absence formalized screen. Bivariable multivariable analyses performed. Of 377 met inclusion criteria, 314 (83%) not more likely experience (19.0% vs 9.2%, p=.02). After controlling for potential confounders, ceased by had greater odds (aOR 2.58, 95% CI 1.15-5.78). known risk desire are unable continue past immediate period increased symptoms.