805: Senescent fetal cells signal human parturition
نویسندگان
چکیده
منابع مشابه
Fetal-to-maternal signaling to initiate parturition.
Multiple processes are capable of activating the onset of parturition; however, the specific contributions of the mother and the fetus to this process are not fully understood. In this issue of the JCI, Gao and colleagues present evidence that steroid receptor coactivators 1 and 2 (SRC-1 and SRC-2) regulate surfactant protein-A (SP-A) and platelet-activating factor (PAF) expression, which incre...
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At parturition, breakdown of extracellular matrix in the fetal membranes may play a part in the rupture of the membranes and in the aetiology of premature rupture, in addition to having a regulatory role in the cell-cell interactions and signalling at the feto-maternal interface to stimulate myometrial contractility. The matrix metalloproteinases (MMPs) are important enzymes for the breakdown o...
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ژورنال
عنوان ژورنال: American Journal of Obstetrics and Gynecology
سال: 2016
ISSN: 0002-9378
DOI: 10.1016/j.ajog.2015.10.854