770-2 Experimental Autoimmune Myocarditis is Associated with Enhanced Vascular Intercellular Adhesion Molecule-1 Expression

Intercellular Adhesion Molecule-1 Expression

Urea induces intercellular adhesion molecule-1 expression

Background The dramatically increased cardiovascular risk in patients with chronic renal disease cannot be explained entirely by traditional cardiovascular risk factors. The continuous exposure of renal patients to elevated levels of urea may contribute to increased inflammation and oxidative stress. While urea may not be directly toxic, many molecules can be carbamylated through cyanate, a rea...

Intercellular adhesion molecule-1 expression in activated eosinophils is associated with mucosal remodeling in nasal polyps

Nasal polyposis (NP) is characterized by chronic mucosal inflammation with infiltrating eosinophils. Eosinophil‑mediated tissue remodeling may be involved in NP pathogenesis; therefore, improved understanding of tissue remodeling may result the identification of novel pathways and therapeutic strategies. The present study aimed to investigate the pathological changes occurring during tissue rem...

Soluble Vascular Cell Adhesion Molecule-1 (VCAM-1) as a Biomarker in the Mouse Model of Experimental Autoimmune Myocarditis (EAM)

Vascular cell adhesion molecule-1 (VCAM-1) is strongly upregulated in hearts of mice with coxsackie virus-induced as well as in patients with viral infection-triggered dilated cardiomyopathy. Nevertheless, the role of its soluble form as a biomarker in inflammatory heart diseases remains unclear. Therefore, we investigated whether plasma levels of soluble VCAM-1 (sVCAM-1) directly correlated wi...

Intercellular Adhesion Molecule (ICAM)-1,