754 A crosstalk between the alpha and beta adrenergic receptors regulates keratinocyte migration
نویسندگان
چکیده
منابع مشابه
Regulation of alpha and beta adrenergic receptors in man.
The sympathetic nervous system is an important regulator of the functional activities of organs such as the heart and peripheral vasculature, and also plays a vital role in modulating responses to stress. The ultimate effects of sympathetic stimulation are mediated by release of noradrenaline (norepinephrine) from nerve terminals which serves to activate the adrenergic receptors at post-synapti...
متن کاملAlpha- and beta-adrenergic receptors: Ahlquist's landmark hypothesis of a single mediator with two receptors.
For those interested in the areas of autonomic physiology and adrenergic pharmacology, there is perhaps no paper more important than Raymond Ahlquist’s seminal contribution in the American Journal of Physiology in 1948 (3). This paper established two fundamental concepts: first, that a single sympathetic mediator could produce both excitatory and inhibitory responses; and second, that adrenergi...
متن کاملBeta-Adrenergic Receptors
ion fluxes in these cells, we have now examined the possibility that the decrease in beta receptor number might be associated with concomitant changes in catecholamine-dependent potassium ion transport. Hypothyroid turkey erythrocytes display decreased sensitivity to isoproterenol-stimulated potassium influx. Half-maximal stimulation of potassium influx occurs at 9.2±+1.7 nM in hypothyroid cell...
متن کاملthe investigation of the relationship between type a and type b personalities and quality of translation
چکیده ندارد.
Interferon regulatory factor 6 regulates keratinocyte migration.
Interferon regulatory factor 6 (Irf6) regulates keratinocyte proliferation and differentiation. In this study, we tested the hypothesis that Irf6 regulates cellular migration and adhesion. Irf6-deficient embryos at 10.5 days post-conception failed to close their wound compared with wild-type embryos. In vitro, Irf6-deficient murine embryonic keratinocytes were delayed in closing a scratch wound...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2016
ISSN: 0022-202X
DOI: 10.1016/j.jid.2016.02.797