7.5% Saline and 7.5% Saline/6% Dextran for Hypovolemic Shock

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7.5% saline and 7.5% saline/6% dextran for hypovolemic shock.

Conventional resuscitation of traumatic hemorrhagic shock involves the intravenous administration of isotonic (normal saline) or slightly hypotonic (lactated Ringer’s, LR) solution beginning in the prehospital setting. Although not conclusive, prior animal and human studies have suggested that alternative resuscitation with hypertonic saline (7.5%) solutions may reduce mortality in these patien...

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75 Lapack

University of Caifornia/Davis 75.

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Hypovolemic shock and resuscitation.

Hypovolemic shock is the manifestation of hypoperfusion from inadequate intravascular volume resulting in cellular hypoxia. Early, effective treatment tailored to the individual patient will minimize morbidity and mortality. The causes and end-organ responses can differ with each patient, requiring an understanding of the underlying physiology and pathophysiology. Treatment always consists of o...

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Hypertonic Saline Dextran Ameliorates Organ Damage in Beagle Hemorrhagic Shock

OBJECTIVE The goal of this study was to investigate the effect of hypertonic saline with 6% Dextran-70 (HSD) resuscitation on organ damage and the resuscitation efficiency of the combination of HSD and lactated ringers (LR) in a model of hemorrhage shock in dogs. METHODS Beagles were bled to hold their mean arterial pressure (MAP) at 50 ± 5 mmHg for 1 h. After hemorrhage, beagles were divided...

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65 - 75 Kar SK.pmd

In the present study, the feeding stage, body parts, development and sex specific activity of Glutathione S-transferases (GSTs) were observed in different mosquito species (Aedes aegypti, Culex quinquefasciatus, Anopheles stephensi, An. culicifacies, An. annularis, An. subpictus, An. vagus). GST activity was assayed spectrophotometrically at 23°C, using a UV Max microplate Reader, to measure th...

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ژورنال

عنوان ژورنال: Journal of Trauma: Injury, Infection & Critical Care

سال: 2011

ISSN: 0022-5282

DOI: 10.1097/ta.0b013e31821a559a