747 PB 105 CLEISTOGAMY GENE ACTION IN SALPIGLOSSIS IS LINKED TO SUGAR METABOLISM

From herkogamy to cleistogamy--development of cleistogamy in periwinkle.

Periwinkle (Catharanthus roseus [L.] G. Don), an important medicinal plant, is an allogamous species in which the stigma is below the anthers. The receptive portion is at the base of the stigmatic head and thus automatic intra-flower self-pollination is excluded. The structure of the flower is of typical reverse herkogamy and pollination occurs through nectar-seeking insects. A few self-pollina...

Marrow fat metabolism is linked to the systemic energy metabolism.

Recent advances in understanding the role of bone in the systemic regulation of energy metabolism indicate that bone marrow cells, adipocytes and osteoblasts, are involved in this process. Marrow adipocytes store significant quantities of fat and produce adipokines, leptin and adiponectin, which are known for their role in the regulation of energy metabolism, whereas osteoblasts produce osteoca...

Glucose metabolism is linked to the inflammatory status of macrophages

Background Macrophages infiltrate adipose tissue at the onset of weight gain and directly contribute to adipose inflammation, insulin resistance, and obesity [1]. The type of fuel substrate utilized by macrophages is central to the formation of obesity, a global epidemic [2]. Our goal is to understand the role of macrophage glucose metabolism in the promotion of inflammation and insulin resista...

Sugar: moving from evidence to action.

Gene Essentiality Is a Quantitative Property Linked to Cellular Evolvability

Gene essentiality is typically determined by assessing the viability of the corresponding mutant cells, but this definition fails to account for the ability of cells to adaptively evolve to genetic perturbations. Here, we performed a stringent screen to assess the degree to which Saccharomyces cerevisiae cells can survive the deletion of ~1,000 individual "essential" genes and found that ~9% of...