7 Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesions

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3 Tesla and 7 Tesla MRI of multiple sclerosis cortical lesions.

Cortical lesions are prevalent in multiple sclerosis but are poorly detected using MRI. The double inversion recovery (DIR) sequence is increasingly used to explore the clinical relevance of cortical demyelination. Here we evaluate the agreement between imaging sequences at 3 Tesla (T) and 7T for the presence and appearance of individual multiple sclerosis cortical lesions. Eleven patients with...

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Onion Peel Appearance in Balos Concentric Sclerosis--a Variant of Multiple Sclerosis.

Balo's concentric sclerosis (BCS) is a variant of multiple sclerosis (MS). It may present as a lesior clinically and radiologically indistinguishable from brain tumour particularly on computerized tomography (CT) scans. Diagnosis only gets clear when magnetic resonance imaging and spectroscopy (MRI & MRS) and brain biopsy is done. We report a case of 30 year old male with progressive headache a...

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Balo's Concentric Sclerosis with Acute Presentation and Co-Existing Multiple Sclerosis-Typical Lesions on MRI

Balo's disease also known as Balo's concentric sclerosis (BCS) is a rare demyelinating disorder which is characterized pathologically and radiologically by concentric rings of demyelinated and relatively myelin-preserved white matter. We describe the case of a 25-year-old female presenting with stroke-like symptoms who was diagnosed with BCS on MRI. At clinical onset, she also showed co-existin...

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Comparison of multiple sclerosis lesions at 1.5 and 3.0 Tesla.

OBJECTIVE To evaluate the relative sensitivity of MR scanning for multiple sclerosis (MS) at 1.5 Tesla (T) and 3.0 T using identical acquisition conditions, as is typical of multicenter clinical trials. METHODS Twenty-five subjects with MS were scanned at 1.5 T and 3.0 T using fast spin echo, and T(1)-weighted SPGR with and without gadolinium contrast injections. Image data, blinded to field ...

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Detecting multiple sclerosis cortical lesions post-mortem using 7 Tesla Magnetic Resonance Imaging

Introduction: Although originally considered a white matter (WM) disease, it is now clear that focal cortical grey matter (GM) pathology is an important component of multiple sclerosis (MS). Presently available magnetic resonance imaging (MRI) techniques fail in detecting the actual amount of cortical lesions (CLs). The reason for such a failure is twofold: (i) the small size of CLs relative to...

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ژورنال

عنوان ژورنال: Annals of Clinical and Translational Neurology

سال: 2018

ISSN: 2328-9503

DOI: 10.1002/acn3.572