منابع مشابه
Medical implications of hyperuricemia.
WHAT IS HYPERURICEMIA? Uric acid is an oxidation product of purine metabolism, which in primates (including humans) is largely eliminated by the kidney and the gut. Most non-primate mammals express uricase, an enzyme that converts serum uric acid into allantoin, which is easily excreted by the kidneys. Nonprimate mammals thus usually have low serum uric acid (SUA) levels (below 2 mg/ dl), while...
متن کاملIntroduction: hyperuricemia and gout.
The pathophysiology of gout is well understood, and effective treatments for acute gout and hyperuricemia leading to gout are widely available. Nonetheless, many patients suffer from severe tophaceous gouty arthritis, adverse effects of medications for gout, and inadequate treatment of hyperuricemia. The incidence of gout is rising in both men and women. The diagnosis and treatment of gout are ...
متن کاملEtiology of hyperuricemia.
Hyperuricemia is a common laboratory finding with significant clinical implications. It is easily detected, but its mechanisms may not be clearly elucidated. A scheme of pathogenesis has been outlined and diagrammed but much is conjectural; therefore, the classification is merely tentative. About 45 diseases or categories of conditions, 20 drugs, and nine states of intoxication have been survey...
متن کاملemodynamics of Hyperuricemia aura
Prolonged hyperuricemia is associated with the development of hypertension, renal arteriolosclerosis, glomerulosclerosis, and tubulointerstitial injury. It confers a greater risk than proteinuria for developing chronic renal disease and is associated with the development of hypertension. Mild chronic hyperuricemia without intrarenal crystal deposition was induced in rats by inhibiting uricase w...
متن کاملHyperuricemia, Cardiovascular Disease, and Hypertension.
In recent years, there has been an increase in the prevalence of hyperuricemia, and the latter has attracted attention as an adult lifestyle-associated disease, together with hypertension, diabetes, and dyslipidemia. Although hyperuricemia is known to be an independent risk factor for hypertension, whether it is an independent risk factor for cardiovascular disease remains controversial. Recent...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2007
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.96.922