#6442 HOW CAN IT BE NEPHROANGIOSCLEROSIS? HE´S BEING TREATED ONLY WITH ONE ANTIHYPERTENSIVE DRUG
نویسندگان
چکیده
Abstract Background and Aims Nephroangiosclerosis is a frequent renal disease due to chronic arterial hypertension it one of the main causes leading replacement therapy. A minority these patients have nephroangiosclerosis although they apparently under control with minimal treatment. Objetives To describe characteristics this group when compared rest histological diagnosis nephroangiosclerosis. Method Observational, retrospective descriptive study. Review 67 as sole in biopsy (consecutive biopsies from 2010 2020). We divided population two different groups according number prescribed antihypertensive drugs: Group 1 (0-1 drugs) vs 2 (≥2 drugs). Results Both had similar demographics function/proteinuria. same adequate/inadequate blood pressure control, but significantly less time hypertension'evolution. The differences (although not statistically significant) are noteworthy: higher percentage global glomerulosclerosis, interstitial fibrosis tubular atrophy than 2. In addition, after 3-years follow-up, there were more requiring hypothesize that factor could explain results be lower use RASi (33.3% 73.9%, P = .003*) history dyslipidemia (62.,5% 22.,2%, p=0,017*). Conclusion Patients maximum drug for its presented marked nephroangiosclerosis, drug, despite evolution degree control. These findings related rate use. Our study reinforces indication first-line treatment population.
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2023
ISSN: ['1460-2385', '0931-0509']
DOI: https://doi.org/10.1093/ndt/gfad063d_6442