6-Ethyl-5-fluoro-2-methoxypyrimidin-4(3H)-one
نویسندگان
چکیده
منابع مشابه
6-Ethyl-5-fluoro-2-methoxypyrimidin-4(3H)-one
In the title compound, C(7)H(9)FN(2)O(2), the meth-oxy and ethyl groups form dihedral angles of 1.4 (2) and 73.5 (3)°, respectively, with the mean plane of the pyrimidine ring. In the crystal structure, two mol-ecules are linked by a pair of N-H⋯O hydrogen bonds, forming a centrosymmetric dimer.
متن کاملCrystal structure of 1-cyclopropyl-2-ethyl-5-fluoro-6- (4-methylpiperazin-1-yl)-1H-benzimidazole.
biological activities,1 and some of them are used as drugs.2,3 In previous studies,4,5 we reported on the synthesis and biological evaluation of 1,2,5(6)-trisubstituted benzimidazoles as antihistaminic and antimicrobial agents. The synthesis of ethyl 1-cyclopropyl-5-fluoro-6-(4-methylpiperazine-1-yl)-1H-benzimidazole-2-acetate (1) was performed according to reported methods.6,7 1-Cyclopropyl-2-...
متن کامل3-(2-Bromoacetyl)-6-fluoro-2H-chromen-2-one
The non-H atoms of the title compound, C(11)H(6)BrFO(3), are essentially coplanar (r.m.s. deviation for all non-H atoms = 0.074 Å). In the crystal, the molecules are linked by C-H⋯O and C-H⋯Br inter-actions.
متن کامل6-Cyclohexylmethyl-5-ethyl-2-[(2-oxo-2-phenylethyl)sulfanyl]pyrimidin-4(3H)-one
In the title compound, C(21)H(26)N(2)O(2)S, the cyclo-hexane ring adopts a chair conformation. The angle at the methyl-ene bridge linking the pyrimidine and cyclo-hexane rings is 113.41 (13)°. This is in the range considered optimal for maximum activity of non-nucleoside reverse transcriptase inhibitors. In the crystal, mol-ecules are connected into centrosymmetric dimers via pairs of N-H⋯O hyd...
متن کامل5-Fluoro-3-(2-phenylhydrazinylidene)indolin-2-one
In the title compound, C(14)H(10)FN(3)O, the six- and five-membered rings of the isatin moiety and the six-membered ring of phenyl-hydrazone are nearly planar with r.m.s. deviations of 0.0003, 0.0004 and 0.007 Å, respectively. The dihedral angle between the phenyl ring and the isatin ring system is 6.09 (9)°. The mol-ecular structure is stabilized by a strong intra-molecular N-H⋯O hydrogen bond...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2009
ISSN: 1600-5368
DOI: 10.1107/s1600536809035430