572 INTRAMYOCARDIAL CALCIFICATION IN APICAL HYPERTROPHIC CARDIOMYOPATHY ASSESSED USING MULTIMODALITY IMAGING: OUR CASE SERIES

نویسندگان

چکیده

Abstract Introduction Apical Hypertrophic Cardiomyopathy (ApHCM) characterized by persistent diastolic apical contraction results in dynamic small-vessel obstruction with microvascular ischemia. Of note, endomyocardial fibrosis (EMF) and calcification are described only few patients. Case presentation We report 5 cases of ApHCM intramyocardial calcification. They presented characteristic ECG pattern at echocardiogram. All patients a preserved ejection fraction (EF), except for one patient mild reduced EF. Global longitudinal strain was 3 Diastolic dysfunction evidenced Right ventricle involvement detected only.On cardiac magnetic resonance, superficial hypo-intense component, compatible calcium deep layer featured late gadolinium enhancement (LGE) related to fibrotic tissue, were revealed. LGE present all the apex. One an aneurysm, high ESC-SCD risk score ICD implantation. Conclusion EMF pathologic hallmarks endocardium myocardium scarring, evolving dystrophic In clinical practice, minority develops calcifications. Our series is largest literature. Analyzing patients’ history, inflammatory trigger evident them, particularly severe chronic kidney disease, diabetes, degree obesity, malaria infection, peripheral microangiopathy form thalassemia. This could demonstrate pathophysiological relation between fibrosis, ischemia due hypertrophy conditions coexistence. A broader case evaluate any correlation their long-term outcome management strategies.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Multimodality imaging in apical hypertrophic cardiomyopathy.

Apical hypertrophic cardiomyopathy (AHCM) is a relatively rare morphologic variant of HCM in which the hypertrophy of myocardium is localized to the left ventricular apex. Symptoms of AHCM might vary from none to others mimic coronary artery disease including acute coronary syndrome, thus resulting in inappropriate hospitalization. Transthoracic echocardiography is the first-line imaging techni...

متن کامل

Intramyocardial calcification in a patient with apical hypertrophic cardiomyopathy.

Intramyocardial calcification is a very rare condition. We report a case of a 72-year-old man with apical hypertrophic cardiomyopathy, who was initially suspected of having a thrombus in the left ventricular apex on echocardiography, but was finally diagnosed as having apical intramyocardial calcification on multidetector computed tomography. The mechanism of developing intramyocardial calcific...

متن کامل

Coexistence of apical hypertrophic cardiomyopathy and endomyocardial fibrosis with calcification: diagnosis using multimodality imaging

A 48-year-old man from West Africa was evaluated for dyspnea. Echocardiography showed an echolucent mass at the left ventricular apex surrounded by a dense ridge of tissue, suggesting endomyocardial fibrosis (EMF). Doppler echocardiography showed restrictive hemodynamics and intramyocardial coronary blood flow at the hypertrophied apex, suggesting apical hypertrophic cardiomyopathy (ApHCM) with...

متن کامل

multimodality imaging in hypertrophic cardiomyopathy associated with anomalous hypertrophied papillary muscles: a case report

conclusions according to our multimodality imaging approach, hypertrophic cardiomyopathy was the most probable diagnosis. case presentation we describe a 73-year-old woman referred to us for consultation because of a giant negative t wave on her electrocardiography. echocardiography revealed diffuse severe hypertrophy associated with hypertrophied anterolateral papillary muscles with a bifid he...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: European Heart Journal Supplements

سال: 2022

ISSN: ['1520-765X', '1554-2815']

DOI: https://doi.org/10.1093/eurheartjsupp/suac121.225