#5069 THE EFFECT OF DIFFERENT DIALYSATE SODIUM CONCENTRATIONS ON AMBULATORY BLOOD PRESSURE AND PULSE WAVE VELOCITY ON HEMODIALYSIS PATIENTS

Abstract Background and Aims Hypertension arterial stiffness are associated with increased morbidity mortality in dialysis patients. The purpose of the present study is to investigate effect sodium concentration dialysate on 72h ambulatory blood pressure stiffness, as well its body weight. Method involved adult patients thrice weekly maintenance hemodialysis program. All initially underwent six sessions 137 meq/l, subsequently another 139 meq/l finally 141 meq/l. At start sixth session at each different concentration, Mobil-o-graph device was placed for order cover 3-day interdialytic interval. parameters evaluated by were peripheral central systolic (pSBP cSBP) diastolic (pDBP cDBP) pulse wave velocity (PWV). screened hydration status lung ultrasound before entering weight actively monitored session. Results Overall, 29 a mean age 57.9±14.9 years included this prospective interventional study. Body did not change significantly between 3 concentrations. There significant increase 6 mmHg pSBP from (from 122.7 125,6 128.3 respectively, p = 0.032). Mean cSBP also 5 110.3 112.6 115.1 0.02). Peripheral DBP 71.4 73.2 74.1 mmHg, ns 73.9 74.8 75.3 ns, respectively), PWV 8.4 8.2 cm/sec, ns). Conclusion increasing causes weight, without PWV.