5-aminolevulinic Acid’s Effects on Immune-related Gene Expression and Acute Hepatopancreatic Necrosis Disease (AHPND) Protection in Pacific White Shrimp <i>Litopenaeus vannamei</i>

نویسندگان

چکیده

5-aminolevulinic acid (5-ALA) is an endogenous non-protein amino that widely used in medicine, pharmacy products, agriculture, and aquaculture. ​In this study, the aim to investigate effects of 5-ALA on feeding Pacific white shrimp (Litopenaeus vannamei) with a diet supplemented their growth performance, immune responses, resistance acute hepatopancreatic necrosis disease (AHPND) caused by Vibrio paraheamolyticus. ​Shrimp were fed different diets, including commercial (control) diets 15 ppm (ALA15) 30 (ALA30) for days before bacteria challenge. ​Anti-lipopolysaccharide factor, crustin, penaeidin3 genes had significantly increased expression level after 5-ALA. ​The mortality rate L. vannamei decreased V. parahaemolyticus infection. ​These results indicated enhanced innate response consequently shrimp's pathogen tolerance. ​Thus, can be as immunostimulant additive cultivation.

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ژورنال

عنوان ژورنال: Fish Pathology

سال: 2021

ISSN: ['0388-788X', '1881-7335']

DOI: https://doi.org/10.3147/jsfp.55.125