495 OR2AT4 activation by a synthetic odorant, stimulates dermcidin production in human hair follicle epithelium and increases follicular resistance to bacterial contamination: A novel antimicrobial folliculitis therapy?
نویسندگان
چکیده
منابع مشابه
hair follicle generation by injecting adult human follicular epithelial and dermal papilla cells in nude mice
objective: objective: dermal papilla and hair epithelial stem cells regulate hair formation and growth cycle. damage to or losing of these cells can cause hair loss. although several studies have claimed to reconstitute hairs using rodent cells in animal model, a stable human hair follicle reconstitution protocol needs more studies. here in this study we evaluated hair induction through injecti...
متن کاملDonor hair follicle preservation by partial follicular unit extraction. A method to optimize hair transplantation.
BACKGROUND There are different stem cell pools located in the hair follicle. OBJECTIVE To try to determine whether follicular units can survive a partial extraction and whether this partial extracted follicular unit can regenerate new hairs. METHODS From five individuals, between 100 and 150 grafts were harvested from the occipital area of the scalp. Suitable grafts were implanted into the ...
متن کاملDifferences in Growth Response of Human Hair Follicle Mesenchymal Stem Cells to Herbal Extracts and a Growth Factor
Background: One of the key questions in biochemistry is why cell becomes aged and what are the involved factors? Why cell growth is stopped after some divisions and cells become senescent? This occurs in a greater frame in the whole body and cells dye after a while. Androgenetic alopecia (AGA) is characterized by a loss or decrease in hair follicle size, which could be related to the loss of ha...
متن کاملThymosin beta4 increases hair growth by activation of hair follicle stem cells.
Thymosin beta4, a 43-amino acid polypeptide that is an important mediator of cell migration and differentiation, also promotes angiogenesis and wound healing. Here, we report that thymosin beta4 stimulates hair growth in normal rats and mice. A specific subset of hair follicular keratinocytes in mouse skin expresses thymosin beta4 in a highly coordinated manner during the hair growth cycle. The...
متن کاملThyrotropin-releasing hormone selectively stimulates human hair follicle pigmentation.
In amphibians, thyrotropin-releasing hormone (TRH) stimulates skin melanophores by inducing secretion of α-melanocyte-stimulating hormone in the pituitary gland. However, it is unknown whether this tripeptide neurohormone exerts any direct effects on pigment cells, namely, on human melanocytes, under physiological conditions. Therefore, we have investigated whether TRH stimulates pigment produc...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2019
ISSN: 0022-202X
DOI: 10.1016/j.jid.2019.03.571