4,5-Dimethoxy-2-nitrobenzhydrol

1 - Fluoro - 2 , 5 - dimethoxy - 4 - nitrobenzene

1-Fluoro-2,5-dimethoxy-4-nitrobenzene was synthesized in 90% yield by the reaction of commercial 2-fluoro-1,4-dimethoxybenzene with nitric acid. The structure was confirmed by X-ray crystallography. The new title compound was characterized by 1H and 13C-NMR, elemental analysis, EI-MS and FT-IR.

ConnCensus Vol. 45 No. 2

trans-2-(2,5-Dimethoxy-4-iodophenyl)cyclopropylamine and trans-2-(2,5-dimethoxy-4-bromophenyl)cyclopropylamine as potent agonists for the 5-HT2 receptor family

A strategy to replace the ethylamine side chain of 2,5-dimethoxy-4-iodoamphetamine (DOI, 1a), and 2,5-dimethoxy-4-bromoamphetamine (DOB, 1b) with a cyclopropylamine moiety was successful in leading to compounds with high affinity at the 5-HT(2) family of receptors; and the more potent stereoisomer of the cyclopropane analogues had the expected (-)-(1R,2S)-configuration. Screening for affinity a...

Limnol. Oceanogr., 45(2), 2000, 309–321

A system was designed for the continuous surface monitoring of hydrological, bio-optical, and biogeochemical properties in the vicinity of the Almeria-Oran jet-front system (Northwestern Mediterranean Sea). This system included a thermosalinograph, a fluorometer, an optical particle counter, and an absorbance-attenuance meter (AC9), allowing the estimation of the absorption [a(l), (m21)] and sc...

Limnol. Oceanogr., 45(2), 2000, 339–349

By factorial field experiments we analyzed the relative effects of increased nutrient (N1P) loading and natural grazing pressure on species composition, carbon storage, and nitrogen retention in the Baltic Sea littoral food web, composed of macroalgae, grazers (snails, isopods, amphipods), and predators (shrimps, crabs, fish). Nitrogen was depleted relative to phosphorus throughout most of the ...