422 Local Anaesthetic Trans-Perineal Prostate Biopsy: Outcomes from Our First 250 Cases

Abstract Aim Trans-perineal ultrasound prostate biopsy (TPBx) with prior multiparametric MRI (mpMRI) represents the standard of care in cancer diagnostic. We present our first experience TPBx unit. also looked at discrepancies between mpMRI and results. Method performed a retrospective analysis collected data from all patients who underwent following March 2021 to June 2022. All had combined systematic targeted biopsies. Results The total 250 TPBx. 10 were already known have cancer. mean age was 69 years. average PSA value PSA: 8.41 ng/ml an density 0.23. 43 previous transrectal ultrasound-guided (TRUS) while 207 naïve. overall detection rate 76 %. In 25 % patients, there some lesion site histology Majority results ISUP grade group 2, 30 case, 3 22 cases, 4 14 1 6% cases 5 2 cases. Conclusions A higher PIRADs score is likely be associated -grade histology. Our acceptable comparison TRUS (76 vs 40 %), however are which suggests additional criteria needed aid decision management (like density).