420: BK virus

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[BK-virus-associated Nephropathy].

The infection by the BK Polyomavirus (BKV) is an emerging problem in kidney transplants that contributes to a chronic loss of kidney grafts, and in which immunosuppression plays a decisive role. Understanding its risk factors and strictly monitoring urine and serological markers of the infection could mitigate the undesirable effects of this disease. In this review, we investigate the clinical ...

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Polyoma BK Virus: An Oncogenic Virus?

We report a case of a 65-year-old gentleman with a history of end stage renal disease who underwent a successful cadaveric donor kidney transplant four years ago. He subsequently developed BK virus nephropathy related to chronic immunosuppressant therapy. Three years later, misfortune struck again, and he developed adenocarcinoma of the bladder.

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Frequency of BK Polyoma Virus in Bladder Cancer

The BK virus a member of the Polyomaviruses family was first isolated from the urine of the kidney recipient. Infection with this virus and infection usually occurs in childhood (5-9 years) but most of the time (90%) of sera are positive and without symptoms. Polyomaviruses including the BK virus have also been suggested to be a contributing factor to some cancers in humans such as brain tumors...

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Bk virus: a clinical review.

We present a review of the clinically oriented literature about BK virus, a relative of JC virus, which is the etiologic agent of progressive multifocal leukoencephalopathy (PML). The kidney, lung, eye, liver, and brain have been proposed as sites of BK virus-associated disease, both primary and reactivated. BK virus has also been detected in tissue specimens from a variety of neoplasms. We bel...

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Vertical transmission of BK virus in pregnancy: A narrative review

Background: Primary infection with the BK virus occurs in the tonsils and is transmitted to other tissues and organs, especially the kidneys, by infecting monocytes. Infection with this virus is rarely associated with clinical disease but reactivating the virus in people who have a suppressed immune system can cause kidney or bladder damage. Due to the importance of activating the BK virus in s...

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ژورنال

عنوان ژورنال: Biology of Blood and Marrow Transplantation

سال: 2007

ISSN: 1083-8791

DOI: 10.1016/j.bbmt.2007.01.050