منابع مشابه
[Interleukin-4 and cardiac fibrosis in patients with heart failure].
Interleukin-4 (IL-4) stimulates inflammatory responses, activates collagen synthesis, promotes fibrosis progression, and inhibits the production of inflammatory cytokines. We studied the relationship between the urinary IL-4 level and levels of markers of cardiac fibrosis and left ventricular volume in 98 patients with heart failure (HF). The left ventricular end-systolic volume index (LVESVI) ...
متن کاملrelease in catecholamine-induced cardiac hypertrophy
Objective: Catecholamines that accompany acute physiological stress are also involved in mediating the development of hypertrophy and failure. However, the cellular mechanisms involved in catecholamine-induced cardiac hypertrophy, particularly Ca + handling, are largely unknown. We therefore investigated the effects of cardiac hypertrophy, produced by isoprenaline, on INa/Ca and sarcoplasmic re...
متن کاملCatecholamine Interactions with the Cardiac Ryanodine Receptor
PDXScholar Dissertations and Theses Dissertations and Theses Let us know how access to this document benefits you. Abstract The cardiac ryanodine receptor (RyR2) is a Ca 2+ ion channel found in the sarcoplasmic reticulum (SR), an intracellular membranous Ca 2+ storage system. It is well known that a destabilization of RyR2 can lead to a Ca 2+ flux out of the SR, which results in an overload of ...
متن کاملPhaeochromocytoma and catecholamine induced cardiomyopathy presenting as heart failure.
Phaeochromocytoma is rare and usually presents as paroxysmal or sustained hypertension; none the less, it can also cause severe acute pulmonary oedema in normotensive individuals. Six patients with phaeochromocytoma presenting in Cornwall and West Devon between 1982 and 1986 are described. Five of them died of pulmonary oedema within 24 hours of the onset of symptoms. At necropsy all five had n...
متن کاملImmobilized catecholamine and cocaine effects on contractility of cardiac muscle.
Isoproterenol, norepinephrine, and epinephrine covalently bound to glass beads exert a positive inotropic effect on isometrically contracting papillary muscles from cats. Immobilized isoproterenol maintains increases in force and velocity of contraction for more than 5 hr. 1 muM Cocaine potentiates the action of immobilized norepinephrine, isoproterenol, and epinephrine, but not of isoprotereno...
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ژورنال
عنوان ژورنال: Japanese Circulation Journal
سال: 1966
ISSN: 0047-1828,1347-4839
DOI: 10.1253/jcj.30.49