3OD – Once-daily (OD) TDF-containing HAART in HIV-1-infected former IVDU-patients receiving opiate substitution: efficacy, tolerability and adherence
نویسندگان
چکیده
منابع مشابه
Efficacy, adherence and tolerability of once daily tenofovir DF-containing antiretroviral therapy in former injecting drug users with HIV-1 receiving opiate treatment: results of a 48-week open-label study
OBJECTIVE To assess efficacy, adherence and tolerability of once daily antiretroviral therapy containing tenofovir disoproxil fumarate (DF) 300 mg in HIV-1-infected former injecting drug users receiving opiate treatment (IVDU). METHODS European, 48-week, open-label, single-arm, multicenter study. Patients were either antiretroviral therapy-naive, restarting therapy after treatment discontinua...
متن کاملPharmacokinetics and tolerability of once- versus twice-daily lopinavir/ritonavir treatment in HIV-1-infected children.
BACKGROUND Once-daily lopinavir/ritonavir (LPV/r) is not approved for treatment of HIV paediatric patients. Once daily treatment in children might serve the same goals of patient comfort and adherence as in adults. METHODS HIV type-1-infected children aged 6 months to 18 years, who were virologically suppressed on an LPV/r-containing regimen, were eligible. Treatment 1 consisted of once-daily...
متن کاملSeminal pharmacokinetics and antiviral efficacy of once-daily maraviroc plus lopinavir/ritonavir in HIV-infected patients.
Sir, Sexual transmission of HIV-1 is currently the major way of viral spread worldwide: the quantification of seminal HIV-1 RNA has been clearly linked to the risk of transmission. The use of highly active antiretroviral treatment, besides providing immunovirological benefits, has been associated with viral control in the genital compartment of males and females. Nevertheless, occasional HIV-1 ...
متن کاملUse of once-daily raltegravir-based HAART in HIV-infected injection drug users
Methods We evaluated HIV-infected IDUs attending an inner city clinic in Vancouver who were receiving RGV-based HAART and methadone within a directly observed therapy program. Follow-up was according to clinical standards, with changes in methadone dose being made as required to achieve clinical stabilization within the first month of HAART. The change in methadone dosing associated with the in...
متن کاملPlasma pharmacokinetics of once-daily abacavir- and lamivudine-containing regimens and week 96 efficacy in HIV-infected Thai children
BACKGROUND Abacavir and lamivudine are approved for once-daily use in HIV-infected adults. Limited pharmacokinetic (PK) data for abacavir and lamivudine in children are available. METHODS A crossover study to compare PK of once- versus twice-daily abacavir and lamivudine was conducted in virologically suppressed HIV-infected Thai children aged <18years, with bodyweight of at least 14 kg, HIV ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the International AIDS Society
سال: 2008
ISSN: 1758-2652
DOI: 10.1186/1758-2652-11-s1-p76