3D-printed vascular networks direct therapeutic angiogenesis in ischaemia
نویسندگان
چکیده
منابع مشابه
3D-printed vascular networks direct therapeutic angiogenesis in ischaemia
Arterial bypass grafts remain the gold standard for the treatment of end-stage ischaemic disease. Yet patients unable to tolerate the cardiovascular stress of arterial surgery or those with unreconstructable disease would benefit from grafts that are able to induce therapeutic angiogenesis. Here, we introduce an approach whereby implantation of 3D-printed grafts containing endothelial-cell-line...
متن کامل3D-Printed Biodegradable Polymeric Vascular Grafts.
Congenital heart defect interventions may benefit from the fabrication of patient-specific vascular grafts because of the wide array of anatomies present in children with cardiovascular defects. 3D printing is used to establish a platform for the production of custom vascular grafts, which are biodegradable, mechanically compatible with vascular tissues, and support neotissue formation and growth.
متن کاملTherapeutic angiogenesis using vascular endothelial growth factor.
Therapeutic angiogenesis using vascular endothelial growth factor can reduce tissue ischemia by simulating the natural process of angiogenesis. Vascular endothelial growth factor not only stimulates endothelial cells to proliferate and migrate, but also mobilizes endothelial progenitor cells and achieves vascular protection. Besides direct administration of angiogenic proteins, plasmids and vir...
متن کاملCharacterization of 3D Printed Fracture Networks
Tracer testing has been used to obtain hydraulic properties in a reservoir system and may help characterize the fracture networks inside the reservoir. Numerous studies at various scales have shown that the distribution of many fracture properties (i.e., length, displacement) follows a power law scaling with some cutoffs. Fractal dimension is useful to evaluate the geometric characteristics of ...
متن کاملHigh-resolution direct 3D printed PLGA scaffolds: print and shrink.
Direct three-dimensional printing (3DP) produces the final part composed of the powder and binder used in fabrication. An advantage of direct 3DP is control over both the microarchitecture and macroarchitecture. Prints which use porogen incorporated in the powder result in high pore interconnectivity, uniform porosity, and defined pore size after leaching. The main limitations of direct 3DP for...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Biomedical Engineering
سال: 2017
ISSN: 2157-846X
DOI: 10.1038/s41551-017-0083