3D printed collagen structures at low concentrations supported by jammed microgels
نویسندگان
چکیده
Improving cell infiltration into engineered scaffolds and decelluarized tissue is needed for developing new effective technologies in regenerative medicine engineering. Significant challenges associated with populating these structures cells have persisted many years. Here we describe a 3D bioprinting method creating precise from natural extracellular matrix at low concentrations that facilitates after printing. We show when printing collagen-1 solutions support medium made jammed microgels, the printer’s basic operating parameters can be used to predict resulting feature size. Microscopic examination of printed features collagen solution undergoes gelation forms network microgels excluded region. Using this print centimeter-scale model gut tube also are able infiltrate structures. Our results demonstrate diversity approaches possible heterogeneously populated
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ژورنال
عنوان ژورنال: Bioprinting
سال: 2021
ISSN: ['2405-8866']
DOI: https://doi.org/10.1016/j.bprint.2020.e00121